| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Prickle-like protein 1 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PRICKLE1 |
| Gene ID: |
144165 |
| Uniprot ID: |
PRIC1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of PRICKLE1 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human PRICKLE1 |
| Function | Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor. |
| Protein Name | Prickle-Like Protein 1Rest/Nrsf-Interacting Lim Domain Protein 1 |
| Database Links | Reactome: R-HSA-4608870 |
| Cellular Localisation | Nucleus MembraneCytoplasmCytosolA Smaller Amount Is Detected In The Cytosol |
| Alternative Antibody Names | Anti-Prickle-Like Protein 1 antibodyAnti-Rest/Nrsf-Interacting Lim Domain Protein 1 antibodyAnti-PRICKLE1 antibodyAnti-RILP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
