| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PRELI domain-containing protein 1, mitochondrial is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PRELID1 |
| Gene ID: |
27166 |
| Uniprot ID: |
PRLD1_HUMAN |
| Specificity: |
This antibody detects endogenous levels of PRELID1 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human PRELID1 |
| Function | Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs. |
| Protein Name | Preli Domain-Containing Protein 1 - Mitochondrial25 Kda Protein Of Relevant Evolutionary And Lymphoid InterestPx19-Like Protein |
| Database Links | Reactome: R-HSA-6803204 |
| Cellular Localisation | MitochondrionMitochondrion Intermembrane Space |
| Alternative Antibody Names | Anti-Preli Domain-Containing Protein 1 - Mitochondrial antibodyAnti-25 Kda Protein Of Relevant Evolutionary And Lymphoid Interest antibodyAnti-Px19-Like Protein antibodyAnti-PRELID1 antibodyAnti-PRELI antibodyAnti-CGI-106 antibodyAnti-SBBI12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
