| Host: |
Rabbit |
| Applications: |
IHC/ELISA |
| Reactivity: |
Human/Mouse |
| Note: |
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Preli Domain-Containing Protein 1-Mitochondrial is suitable for use in Immunohistochemistry and ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
| Purification: |
Antigen affinity purification |
| Concentration: |
0.9 mg/mL |
| Dilution Range: |
IHC 1:30-1:150 |
| Storage Instruction: |
Store at-20°C for long term, and avoid freeze-thaw cycles. |
| Tissue Specificity | Highly expressed in fetal liver.less expressed in fetal brain, lung, and kidney. At the adult stage, expression is drastically reduced in the liver but highly expressed in the spleen, brain, lung, lymph nodes and peripheral blood leukocytes. |
| Function | Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs. |
| Protein Name | Preli Domain-Containing Protein 1 - Mitochondrial25 Kda Protein Of Relevant Evolutionary And Lymphoid InterestPx19-Like Protein |
| Database Links | Reactome: R-HSA-6803204 |
| Cellular Localisation | MitochondrionMitochondrion Intermembrane Space |
| Alternative Antibody Names | Anti-Preli Domain-Containing Protein 1 - Mitochondrial antibodyAnti-25 Kda Protein Of Relevant Evolutionary And Lymphoid Interest antibodyAnti-Px19-Like Protein antibodyAnti-PRELID1 antibodyAnti-PRELI antibodyAnti-CGI-106 antibodyAnti-SBBI12 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
