| Short Description : | Rabbit polyclonal anti-Thioredoxin-dependent peroxide reductase, mitochondrial (44-93 aa) for use in WB, IHC, IP, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IP/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC-P 1:50-300IP 1:50-200ELISA 1:20000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PRDX3 |
| Gene ID: | 10935 |
| Uniprot ID: | PRDX3_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human PRX III at the amino acid range 44-93 |
| Immunogen Region: | 44-93 aa |
| Specificity: | PRX III Polyclonal Antibody detects endogenous levels of PRX III protein. |
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. Required for the maintenance of physical strength. |
| Protein Name | Thioredoxin-Dependent Peroxide Reductase - MitochondrialAntioxidant Protein 1Aop-1Hbc189Peroxiredoxin IiiPrx-IiiPeroxiredoxin-3Protein Mer5 HomologThioredoxin-Dependent Peroxiredoxin 3 |
| Database Links | Reactome: R-HSA-3299685 |
| Cellular Localisation | MitochondrionCytoplasmEarly EndosomeLocalizes To Early Endosomes In A Rps6kc1-Dependent Manner |
| Alternative Antibody Names | Anti-Thioredoxin-Dependent Peroxide Reductase - Mitochondrial antibodyAnti-Antioxidant Protein 1 antibodyAnti-Aop-1 antibodyAnti-Hbc189 antibodyAnti-Peroxiredoxin Iii antibodyAnti-Prx-Iii antibodyAnti-Peroxiredoxin-3 antibodyAnti-Protein Mer5 Homolog antibodyAnti-Thioredoxin-Dependent Peroxiredoxin 3 antibodyAnti-PRDX3 antibodyAnti-AOP1 antibody |
Information sourced from Uniprot.org
