| Host: |
Goat |
| Applications: |
Pep-ELISA/WB/IHC |
| Reactivity: |
Human/Mouse/Rat/Dog/Pig/Cow |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-PRDX1 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-0.1-0.3µg/mlIHC-2.5µg/mlELISA-antibody detection limit dilution 1:8000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
PRDX1 |
| Gene ID: |
5052 |
| Uniprot ID: |
PRDX1_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_859048.1 |
| Specificity: |
Reported variants represent identical protein (NP_002565.1, NP_859047.1, NP_859048.1). |
| Immunogen Sequence: |
SDPKRTIAQDYG |
| Function | Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation. |
| Protein Name | Peroxiredoxin-1Natural Killer Cell-Enhancing Factor ANkef-AProliferation-Associated Gene ProteinPagThioredoxin Peroxidase 2Thioredoxin-Dependent Peroxide Reductase 2Thioredoxin-Dependent Peroxiredoxin 1 |
| Database Links | Reactome: R-HSA-3299685Reactome: R-HSA-5628897Reactome: R-HSA-8862803Reactome: R-HSA-9818027 |
| Cellular Localisation | CytoplasmMelanosomeIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage Iv |
| Alternative Antibody Names | Anti-Peroxiredoxin-1 antibodyAnti-Natural Killer Cell-Enhancing Factor A antibodyAnti-Nkef-A antibodyAnti-Proliferation-Associated Gene Protein antibodyAnti-Pag antibodyAnti-Thioredoxin Peroxidase 2 antibodyAnti-Thioredoxin-Dependent Peroxide Reductase 2 antibodyAnti-Thioredoxin-Dependent Peroxiredoxin 1 antibodyAnti-PRDX1 antibodyAnti-PAGA antibodyAnti-PAGB antibodyAnti-TDPX2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
