| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PRDM15 (1268-1507) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PRDM15 |
| Gene ID: |
63977 |
| Uniprot ID: |
PRD15_HUMAN |
| Immunogen Region: |
1268-1507 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1268-1507 of human PRDM15 (NP_071398.3). |
| Immunogen Sequence: |
IDASSIGIVQPELTLEQEDL AEGKHGKAAKRSHKRKQKPE EEAGAPVPEDATFSEYSEKE TEFTGSVGDETNSAVQSIQQ VVVTLGDPNVTTPSSSVGLT NITVTPITTAAATQFTNLQP VAVGHLTTPERQLQLDNSIL TVTFDTVSGSAMLHNRQNDV QIHPQPEASNPQSVAHFINL TTLVNSITPLGSQLSDQHPL TWRAVPQTDVLPPSQPQAPP QQAAQPQVQAEQQQQQMYS |
| Tissue Specificity | Detected in all tissues examined. |
| Function | Sequence-specific DNA-binding transcriptional regulator. Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision. Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways, respectively, that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs). Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in their promoter regions. Involved in early embryo development. Also plays a role in induced pluripotent stem cells (iPSCs) reprogramming. |
| Protein Name | Pr Domain Zinc Finger Protein 15Pr Domain-Containing Protein 15Zinc Finger Protein 298 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pr Domain Zinc Finger Protein 15 antibodyAnti-Pr Domain-Containing Protein 15 antibodyAnti-Zinc Finger Protein 298 antibodyAnti-PRDM15 antibodyAnti-C21orf83 antibodyAnti-ZNF298 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
