| Host: | Rabbit |
| Applications: | WB/ELISA/IHC |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Serine/threonine-protein phosphatase 2A regulatory subunit B subunit gamma (165-214 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPP2R3C |
| Gene ID: | 55012 |
| Uniprot ID: | P2R3C_HUMAN |
| Immunogen Region: | 165-214 aa |
| Specificity: | PPP2R3C Polyclonal Antibody detects endogenous levels of PPP2R3C protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human PPP2R3C at the amino acid range 165-214 |
| Function | May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells. |
| Protein Name | Serine/Threonine-Protein Phosphatase 2a Regulatory Subunit B'' Subunit GammaProtein Phosphatase Subunit G5prRhabdomyosarcoma Antigen Mu-Rms-40.6a/6c |
| Cellular Localisation | NucleusCytoplasmExcluded From The NucleoliLocalization Is Cell Cycle-DependentLocalizes To The Cytoplasm During Cytokinesis |
| Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 2a Regulatory Subunit B'' Subunit Gamma antibodyAnti-Protein Phosphatase Subunit G5pr antibodyAnti-Rhabdomyosarcoma Antigen Mu-Rms-40.6a/6c antibodyAnti-PPP2R3C antibodyAnti-C14orf10 antibodyAnti-G5PR antibody |
Information sourced from Uniprot.org