Host: | Rabbit |
Applications: | WB/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
Purification: | Affinity purification |
Concentration: | Lot specific |
Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
Gene Symbol: | PPP2R3C |
Gene ID: | 55012 |
Uniprot ID: | P2R3C_HUMAN |
Immunogen Region: | 1-160 aa |
Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human PPP2R3C (NP_060387.2). |
Immunogen Sequence: | MDWKEVLRRRLATPNTCPNK KKSEQELKDEEMDLFTKYYS EWKGGRKNTNEFYKTIPRFY YRLPAEDEVLLQKLREESRA VFLQRKSRELLDNEELQNLW FLLDKHQTPPMIGEEAMINY ENFLKVGEKAGAKCKQFFTA KVFAKLLHTDSYGRISIMQF |
Tissue Specificity | Ubiquitously expressed in brain and other tissues. |
Function | May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells. |
Protein Name | Serine/Threonine-Protein Phosphatase 2a Regulatory Subunit B'' Subunit GammaProtein Phosphatase Subunit G5prRhabdomyosarcoma Antigen Mu-Rms-40.6a/6c |
Cellular Localisation | NucleusCytoplasmExcluded From The NucleoliLocalization Is Cell Cycle-DependentLocalizes To The Cytoplasm During Cytokinesis |
Alternative Antibody Names | Anti-Serine/Threonine-Protein Phosphatase 2a Regulatory Subunit B'' Subunit Gamma antibodyAnti-Protein Phosphatase Subunit G5pr antibodyAnti-Rhabdomyosarcoma Antigen Mu-Rms-40.6a/6c antibodyAnti-PPP2R3C antibodyAnti-C14orf10 antibodyAnti-G5PR antibody |
Information sourced from Uniprot.org