Anti-PPP1R14A antibody (1-147) (STJ112199)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PPP1R14A (1-147) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPP1R14A |
| Gene ID | 94274 |
| Uniprot ID | PP14A_HUMAN |
| Immunogen Region | 1-147 |
| Immunogen Sequence | MAAQRLGKRVLSKLQSPSRA RGPGGSPGGLQKRHARVTVK YDRRELQRRLDVEKWIDGRL EELYRGMEADMPDEINIDEL LELESEEERSRKIQGLLKSC GKPVEDFIQELLAKLQGLHR QPGLRQPSPSHDGSLSPLQD RARTAHP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-147 of human PPP1R14A (NP_150281.1). |
Additional Info
| Tissue Specificity | Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. |
| Function | Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 14a17 Kda Pkc-Potentiated Inhibitory Protein Of Pp1Protein Kinase C-Potentiated Inhibitor Protein Of 17 KdaCpi-17 |
| Database Links | Reactome: R-HSA-5625740 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Protein Phosphatase 1 Regulatory Subunit 14a antibodyAnti-17 Kda Pkc-Potentiated Inhibitory Protein Of Pp1 antibodyAnti-Protein Kinase C-Potentiated Inhibitor Protein Of 17 Kda antibodyAnti-Cpi-17 antibodyAnti-PPP1R14A antibodyAnti-CPI17 antibodyAnti-PPP1INL antibody |
Information sourced from Uniprot.org