| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-RING-type E3 ubiquitin-protein ligase PPIL2 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PPIL2 |
| Gene ID: |
23759 |
| Uniprot ID: |
PPIL2_HUMAN |
| Specificity: |
This antibody detects endogenous levels of PPIL2 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human PPIL2 |
| Function | Has a ubiquitin-protein ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation. May also function as a chaperone, playing a role in transport to the cell membrane of BSG/Basigin for instance. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). |
| Protein Name | Ring-Type E3 Ubiquitin-Protein Ligase Ppil2Cyc4Cyclophilin-60Cyclophilin-Like Protein Cyp-60Cyp60Hcyp-60Probable Inactive Peptidyl-Prolyl Cis-Trans Isomerase-Like 2PpiaseRotamase Ppil2 |
| Database Links | Reactome: R-HSA-210991Reactome: R-HSA-72163 |
| Cellular Localisation | NucleusMay Also Localize To The Cytoplasm And The Cell Membrane |
| Alternative Antibody Names | Anti-Ring-Type E3 Ubiquitin-Protein Ligase Ppil2 antibodyAnti-Cyc4 antibodyAnti-Cyclophilin-60 antibodyAnti-Cyclophilin-Like Protein Cyp-60 antibodyAnti-Cyp60 antibodyAnti-Hcyp-60 antibodyAnti-Probable Inactive Peptidyl-Prolyl Cis-Trans Isomerase-Like 2 antibodyAnti-Ppiase antibodyAnti-Rotamase Ppil2 antibodyAnti-PPIL2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
