| Short Description : | Rabbit polyclonal PPIH (1-177) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PPIH |
| Gene ID: | 10465 |
| Uniprot ID: | PPIH_HUMAN |
| Immunogen Region: | 1-177 |
| Immunogen Sequence: | MAVANSSPVNPVVFFDVSIG GQEVGRMKIELFADVVPKTA ENFRQFCTGEFRKDGVPIGY KGSTFHRVIKDFMIQGGDFV NGDGTGVASIYRGPFADENF KLRHSAPGLLSMANSGPSTN GCQFFITCSKCDWLDGKHVV FGKIIDGLLVMRKIENVPTG PNNKPKLPVVISQCGEM |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-177 of human PPIH (NP_006338.1). |
| Function | PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone. |
| Protein Name | Peptidyl-Prolyl Cis-Trans Isomerase HPpiase HRotamase HSmall Nuclear Ribonucleoprotein Particle-Specific Cyclophilin HCyphU-Snrnp-Associated Cyclophilin Snucyp-20Usa-Cyp |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-9692916 |
| Cellular Localisation | Nucleus SpeckleCytoplasmColocalizes With Spliceosomal SnrnpsA Small Proportion May Also Be Cytoplasmic |
| Alternative Antibody Names | Anti-Peptidyl-Prolyl Cis-Trans Isomerase H antibodyAnti-Ppiase H antibodyAnti-Rotamase H antibodyAnti-Small Nuclear Ribonucleoprotein Particle-Specific Cyclophilin H antibodyAnti-Cyph antibodyAnti-U-Snrnp-Associated Cyclophilin Snucyp-20 antibodyAnti-Usa-Cyp antibodyAnti-PPIH antibodyAnti-CYP20 antibodyAnti-CYPH antibody |
Information sourced from Uniprot.org
