Anti-PPIH antibody (1-177) (STJ114065)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PPIH (1-177) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPIH |
| Gene ID | 10465 |
| Uniprot ID | PPIH_HUMAN |
| Immunogen Region | 1-177 |
| Immunogen Sequence | MAVANSSPVNPVVFFDVSIG GQEVGRMKIELFADVVPKTA ENFRQFCTGEFRKDGVPIGY KGSTFHRVIKDFMIQGGDFV NGDGTGVASIYRGPFADENF KLRHSAPGLLSMANSGPSTN GCQFFITCSKCDWLDGKHVV FGKIIDGLLVMRKIENVPTG PNNKPKLPVVISQCGEM |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-177 of human PPIH (NP_006338.1). |
Additional Info
| Function | PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. Participates in pre-mRNA splicing. May play a role in the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. May act as a chaperone. |
| Protein Name | Peptidyl-Prolyl Cis-Trans Isomerase HPpiase HRotamase HSmall Nuclear Ribonucleoprotein Particle-Specific Cyclophilin HCyphU-Snrnp-Associated Cyclophilin Snucyp-20Usa-Cyp |
| Database Links | Reactome: R-HSA-72163Reactome: R-HSA-9692916 |
| Cellular Localisation | Nucleus SpeckleCytoplasmColocalizes With Spliceosomal SnrnpsA Small Proportion May Also Be Cytoplasmic |
| Alternative Antibody Names | Anti-Peptidyl-Prolyl Cis-Trans Isomerase H antibodyAnti-Ppiase H antibodyAnti-Rotamase H antibodyAnti-Small Nuclear Ribonucleoprotein Particle-Specific Cyclophilin H antibodyAnti-Cyph antibodyAnti-U-Snrnp-Associated Cyclophilin Snucyp-20 antibodyAnti-Usa-Cyp antibodyAnti-PPIH antibodyAnti-CYP20 antibodyAnti-CYPH antibody |
Information sourced from Uniprot.org