Immunohistochemical analysis of paraffin-embedded Mouse Brain Tissue using PPAR Delta Mouse mAb diluted at 1:200.

Anti-PPARD antibody [2F9] (STJ97707)

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STJ97707
£49.00 - £261.00
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Short Description :Mouse monoclonal anti-Peroxisome proliferator-activated receptor delta for use in IF and IHC in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IF/IHC
Host:Mouse
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :2F9
Isotype:IgG1
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Dilution Range:IF 1:50-200
IHC 1:100-200
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:PPARD
Gene ID:5467
Uniprot ID:PPARD_HUMAN
Immunogen:Recombinant Protein of PPAR Delta of PPAR Delta
Specificity:PPAR Delta protein detects endogenous levels of PPAR Delta
Post Translational Modifications 'Lys-48'-linked polyubiquitinated.leading to proteasomal degradation. Deubiquitinated and stabilized by OTUD3.
Function Ligand-activated transcription factor key mediator of energy metabolism in adipose tissues. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand.
Protein Name Peroxisome Proliferator-Activated Receptor Delta
Ppar-Delta
Nuci
Nuclear Hormone Receptor 1
Nuc1
Nuclear Receptor Subfamily 1 Group C Member 2
Peroxisome Proliferator-Activated Receptor Beta
Ppar-Beta
Database Links Reactome: R-HSA-200425
Reactome: R-HSA-383280
Reactome: R-HSA-5362517
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Peroxisome Proliferator-Activated Receptor Delta antibody
Anti-Ppar-Delta antibody
Anti-Nuci antibody
Anti-Nuclear Hormone Receptor 1 antibody
Anti-Nuc1 antibody
Anti-Nuclear Receptor Subfamily 1 Group C Member 2 antibody
Anti-Peroxisome Proliferator-Activated Receptor Beta antibody
Anti-Ppar-Beta antibody
Anti-PPARD antibody
Anti-NR1C2 antibody
Anti-PPARB antibody

Information sourced from Uniprot.org

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