| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-POU4F3 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:8000.WB: Approx 40kDa band observed in Human and Mouse Heart lysates (calculated MW of 37.1kDa according to Human NP_002691.1). Recommended concentration: 0.2-0.6µg/ml. |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | POU4F3 |
| Gene ID: | 5459 |
| Uniprot ID: | PO4F3_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_002691.1 |
| Specificity: | This antibody is expected not to cross-react to the similar POU4F1 and POU4F2. |
| Immunogen Sequence: | EAAYREKNSKPE |
| Function | Acts as a transcriptional activator. Acts by binding to sequences related to the consensus octamer motif 5'-ATGCAAAT-3' in the regulatory regions of its target genes. Involved in the auditory system development, required for terminal differentiation of hair cells in the inner ear. |
| Protein Name | Pou Domain - Class 4 - Transcription Factor 3Brain-Specific Homeobox/Pou Domain Protein 3cBrain-3cBrn-3c |
| Cellular Localisation | NucleusCytoplasmPreferentially Localized In The Nucleus |
| Alternative Antibody Names | Anti-Pou Domain - Class 4 - Transcription Factor 3 antibodyAnti-Brain-Specific Homeobox/Pou Domain Protein 3c antibodyAnti-Brain-3c antibodyAnti-Brn-3c antibodyAnti-POU4F3 antibodyAnti-BRN3C antibody |
Information sourced from Uniprot.org