| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human/Mouse/Rat/Dog/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-POU2F2/OCT2 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx 55kDa band observed in Human Thymus and Tonsil lysates (calculated MW of 49.5kDa according to NP_002689.1). Recommended concentration: 0.5-1.5µg/ml.An additional band of unknown |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | POU2F2 |
| Gene ID: | 5452 |
| Uniprot ID: | PO2F2_HUMAN |
| Immunogen Region: | Internal |
| Accession Number: | NP_002689.1 |
| Immunogen Sequence: | SPTGPSTKIKAED |
| Function | Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates IL6 expression in B cells with POU2AF1. Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5: Activates the U2 small nuclear RNA (snRNA) promoter. |
| Protein Name | Pou Domain - Class 2 - Transcription Factor 2Lymphoid-Restricted Immunoglobulin Octamer-Binding Protein Nf-A2Octamer-Binding Protein 2Oct-2Octamer-Binding Transcription Factor 2Otf-2 |
| Database Links | Reactome: R-HSA-6807505 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Pou Domain - Class 2 - Transcription Factor 2 antibodyAnti-Lymphoid-Restricted Immunoglobulin Octamer-Binding Protein Nf-A2 antibodyAnti-Octamer-Binding Protein 2 antibodyAnti-Oct-2 antibodyAnti-Octamer-Binding Transcription Factor 2 antibodyAnti-Otf-2 antibodyAnti-POU2F2 antibodyAnti-OCT2 antibodyAnti-OTF2 antibody |
Information sourced from Uniprot.org