Anti-POSTN/OSF-2 antibody (Met1-Gln781) [1A073] (STJA0021911)

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STJA0021911
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Host: Mouse
Applications: ELISA/IHC/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description : Mouse monoclonal anti-Periostin (Met1-Gln781) for use in ELISA, IHC and WB in Human samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : 1A073
Conjugation: Unconjugated
Isotype: IgG1
Formulation: 0.01M PBS, pH 7.4.
Purification: Protein A/G purified from cell culture supernatant
Concentration: 1 mg/mL
Storage Instruction: Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months
Gene Symbol: POSTN
Gene ID: 10631
Uniprot ID: POSTN_HUMAN
Immunogen Region: Met1-Gln781
Immunogen: Mammalian cells-derived recombinant Human POSTN/OSF-2 (Met1-Gln781)
Post Translational Modifications Gamma-carboxylation is controversial. Gamma-carboxyglutamated.gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation.this may be required for calcium binding. According to a more recent report, does not contain vitamin K-dependent gamma-carboxyglutamate residues.
Function Induces cell attachment and spreading and plays a role in cell adhesion. Enhances incorporation of BMP1 in the fibronectin matrix of connective tissues, and subsequent proteolytic activation of lysyl oxidase LOX.
Protein Name Periostin
Pn
Osteoblast-Specific Factor 2
Osf-2
Database Links
Cellular Localisation Golgi Apparatus
Secreted
Extracellular Space
Extracellular Matrix
Colocalizes With Bmp1 In The Golgi
Alternative Antibody Names Anti-Periostin antibody
Anti-Pn antibody
Anti-Osteoblast-Specific Factor 2 antibody
Anti-Osf-2 antibody
Anti-POSTN antibody
Anti-OSF2 antibody

Information sourced from Uniprot.org

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