| Short Description : | Goat polyclonal antibody anti-PON2 (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications: | Pep-ELISA/WB/IHC |
| Host: | Goat |
| Reactivity: | Human/Rat/Pig/Dog |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 0.5 mg/mL |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:32000.WB: Approx 40kDa double band observed in lysates of HepG2 (calculated MW of 39.4kDa according to NP_000296.2 and of 38.0kDa according to NP_001018171.1). Recommended concentration: 0.2-0.6 |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PON2 |
| Gene ID: | 5445 |
| Uniprot ID: | PON2_HUMAN |
| Accession Number: | NP_000296.2; NP_001018171.1 |
| Immunogen Region: | Internal |
| Immunogen Sequence: | EKPRARELRIS |
| Specificity: | This antibody is expected to recognize isoforms 1 and 2 (NP_000296.2; NP_001018171.1). |
| Post Translational Modifications | The signal sequence is not cleaved. |
| Function | Capable of hydrolyzing lactones and a number of aromatic carboxylic acid esters. Has antioxidant activity. Is not associated with high density lipoprotein. Prevents LDL lipid peroxidation, reverses the oxidation of mildly oxidized LDL, and inhibits the ability of MM-LDL to induce monocyte chemotaxis. |
| Protein Name | Serum Paraoxonase/Arylesterase 2Pon 2Aromatic Esterase 2A-Esterase 2Serum Aryldialkylphosphatase 2 |
| Database Links | Reactome: R-HSA-2142688 |
| Cellular Localisation | MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Serum Paraoxonase/Arylesterase 2 antibodyAnti-Pon 2 antibodyAnti-Aromatic Esterase 2 antibodyAnti-A-Esterase 2 antibodyAnti-Serum Aryldialkylphosphatase 2 antibodyAnti-PON2 antibody |
Information sourced from Uniprot.org
