| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-PON1/paraoxonase 1 (Internal) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-1-3µg/mlELISA-antibody detection limit dilution 1:2000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
PON1 |
| Gene ID: |
5444 |
| Uniprot ID: |
PON1_HUMAN |
| Immunogen Region: |
Internal |
| Accession Number: |
NP_000437.3 |
| Immunogen Sequence: |
EEPKVTQVYAEN |
| Post Translational Modifications | Glycosylated. The signal sequence is not cleaved. Present in two forms, form B contains a disulfide bond, form A does not. |
| Function | Hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. |
| Protein Name | Serum Paraoxonase/Arylesterase 1Pon 1 Aromatic Esterase 1A-Esterase 1K-45Serum Aryldialkylphosphatase 1 |
| Database Links | Reactome: R-HSA-2142688Reactome: R-HSA-9754706 |
| Cellular Localisation | SecretedExtracellular Space |
| Alternative Antibody Names | Anti-Serum Paraoxonase/Arylesterase 1 antibodyAnti-Pon 1 antibodyAnti-Aromatic Esterase 1 antibodyAnti-A-Esterase 1 antibodyAnti-K-45 antibodyAnti-Serum Aryldialkylphosphatase 1 antibodyAnti-PON1 antibodyAnti-PON antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
