| Host: | Rabbit |
| Applications: | ELISA/IHC/IP/WB |
| Reactivity: | Human/Monkey/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-POMT2 (500-560) is suitable for use in ELISA, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.55-0.75 µg/µl |
| Dilution Range: | WB: 1:500 DB: 1:10, 000 ELISA: 1:10, 000 IP: 1:200 IHC: 1:1000 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: | POMT2 |
| Gene ID: | 29954 |
| Uniprot ID: | POMT2_HUMAN |
| Immunogen Region: | 500-560 |
| Immunogen: | Synthetic peptide taken within amino acid region 500-560 on human POMT2 protein. |
| Tissue Specificity | Highly expressed in testis.detected at low levels in most tissues. |
| Post Translational Modifications | N-glycosylated. |
| Function | Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins. |
| Protein Name | Protein O-Mannosyl-Transferase 2 Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 2 |
| Database Links | Reactome: R-HSA-5083629 Reactome: R-HSA-5083633 Reactome: R-HSA-5173105 |
| Cellular Localisation | Endoplasmic Reticulum Membrane Multi-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Protein O-Mannosyl-Transferase 2 antibody Anti-Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 2 antibody Anti-POMT2 antibody |
Information sourced from Uniprot.org