Anti-POMT2 antibody (177-227 aa) (STJ195740)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human POMT2 at the amino acid range 177-227
General Information
| Short Description | Rabbit polyclonal anti-Protein O-mannosyl-transferase 2 (177-227 aa) for use in WB and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | POMT2 |
| Gene ID | 29954 |
| Uniprot ID | POMT2_HUMAN |
| Immunogen | Synthesized peptide derived from the human POMT2 at the amino acid range 177-227 |
| Immunogen Region | 177-227 aa |
| Specificity | This antibody detects endogenous levels of POMT2 at Human/Mouse |
Additional Info
| Post Translational Modifications | N-glycosylated. |
| Function | Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient. Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins. |
| Protein Name | Protein O-Mannosyl-Transferase 2Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 2 |
| Database Links | Reactome: R-HSA-5083629Reactome: R-HSA-5083633Reactome: R-HSA-5173105 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Protein O-Mannosyl-Transferase 2 antibodyAnti-Dolichyl-Phosphate-Mannose--Protein Mannosyltransferase 2 antibodyAnti-POMT2 antibody |
Information sourced from Uniprot.org