| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Gene Symbol: | POLM |
| Gene ID: | 27434 |
| Uniprot ID: | DPOLM_HUMAN |
| Immunogen Region: | 1-180 aa |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human POLM (NP_037416.1). |
| Immunogen Sequence: | MLPKRRRARVGSPSGDAASS TPPSTRFPGVAIYLVEPRMG RSRRAFLTGLARSKGFRVLD ACSSEATHVVMEETSAEEAV SWQERRMAAAPPGCTPPALL DISWLTESLGAGQPVPVECR HRLEVAGPRKGPLSPAWMPA YACQRPTPLTHHNTGLSEAL EILAEAAGFEGSEGRLLTFC |
| Tissue Specificity | Expressed in a number of tissues. Abundant in thymus. |
| Function | Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination. |
| Protein Name | Dna-Directed Dna/Rna Polymerase MuPol MuTerminal Transferase |
| Database Links | Reactome: R-HSA-5693571 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Dna-Directed Dna/Rna Polymerase Mu antibodyAnti-Pol Mu antibodyAnti-Terminal Transferase antibodyAnti-POLM antibodyAnti-polmu antibody |
Information sourced from Uniprot.org