Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Polymerase delta-interacting protein 3 (348-397 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | POLDIP3 |
Gene ID: | 84271 |
Uniprot ID: | PDIP3_HUMAN |
Immunogen Region: | 348-397 aa |
Specificity: | POLDIP3 Polyclonal Antibody detects endogenous levels of POLDIP3 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human POLDIP3 at the amino acid range 348-397 |
Function | Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export.probably mediated by association with the TREX complex. |
Protein Name | Polymerase Delta-Interacting Protein 346 Kda Dna Polymerase Delta Interaction ProteinP46S6k1 Aly/Ref-Like TargetSkar |
Database Links | Reactome: R-HSA-159236Reactome: R-HSA-72187Reactome: R-HSA-73856 |
Cellular Localisation | NucleusNucleus SpeckleCytoplasmNucleocytoplasmic Shuttling Protein |
Alternative Antibody Names | Anti-Polymerase Delta-Interacting Protein 3 antibodyAnti-46 Kda Dna Polymerase Delta Interaction Protein antibodyAnti-P46 antibodyAnti-S6k1 Aly/Ref-Like Target antibodyAnti-Skar antibodyAnti-POLDIP3 antibodyAnti-KIAA1649 antibodyAnti-PDIP46 antibody |
Information sourced from Uniprot.org