| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | POC1A |
| Gene ID: | 25886 |
| Uniprot ID: | POC1A_HUMAN |
| Immunogen Region: | 138-407 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 138-407 of human POC1A (NP_056241.3). |
| Immunogen Sequence: | LFSLSQHINWVRCAKFSPDG RLIVSASDDKTVKLWDKSSR ECVHSYCEHGGFVTYVDFHP SGTCIAAAGMDNTVKVWDVR THRLLQHYQLHSAAVNGLSF HPSGNYLITASSDSTLKILD LMEGRLLYTLHGHQGPATTV AFSRTGEYFASGGSDEQVMV WKSNFDIVDHGEVTKVPRPP ATLASSMGNLPEVDFPVPPG RGRSVESVQSQPQEPVSVPQ TLTSTLEHIVGQLDVLTQT |
| Function | Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1B to ensure centriole integrity and proper mitotic spindle formation. |
| Protein Name | Poc1 Centriolar Protein Homolog A Pix2 Proteome Of Centriole Protein 1a Wd Repeat-Containing Protein 51a |
| Cellular Localisation | Cytoplasm Cytoskeleton Microtubule Organizing Center Centrosome Centriole Cilium Basal Body Spindle Pole Component Of Both Mother And Daughter Centrioles |
| Alternative Antibody Names | Anti-Poc1 Centriolar Protein Homolog A antibody Anti-Pix2 antibody Anti-Proteome Of Centriole Protein 1a antibody Anti-Wd Repeat-Containing Protein 51a antibody Anti-POC1A antibody Anti-WDR51A antibody |
Information sourced from Uniprot.org