| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Patatin-like phospholipase domain-containing protein 6 (1031-1080 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC-P 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PNPLA6 |
| Gene ID: | 10908 |
| Uniprot ID: | PLPL6_HUMAN |
| Immunogen Region: | 1031-1080 aa |
| Specificity: | NTE Polyclonal Antibody detects endogenous levels of NTE protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the Internal region of human PNPLA6 at the amino acid range 1031-1080 |
| Post Translational Modifications | Glycosylated. |
| Function | Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Catalyzes the hydrolysis of several naturally occurring membrane-associated lipids. Hydrolyzes lysophospholipids and monoacylglycerols, preferring the 1-acyl to the 2-acyl isomer. Does not catalyze hydrolysis of di- or triacylglycerols or fatty acid amides. |
| Protein Name | Patatin-Like Phospholipase Domain-Containing Protein 6Neuropathy Target Esterase |
| Database Links | Reactome: R-HSA-6814848 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type Iii Membrane Protein |
| Alternative Antibody Names | Anti-Patatin-Like Phospholipase Domain-Containing Protein 6 antibodyAnti-Neuropathy Target Esterase antibodyAnti-PNPLA6 antibodyAnti-NTE antibody |
Information sourced from Uniprot.org