| Host: | Mouse |
| Applications: | WB/IHC/ICC/IF |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-PNP for use in WB, IHC, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | 7G5 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Formulation: | Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. NA |
| Purification: | Lyophilized |
| Concentration: | Adding 0.2 mL of distilled water =f 500 Mu g/mL. |
| Storage Instruction: | Store at-20°C for up to 1 year. Minimise freeze-thaw cycles. |
| Gene Symbol: | PNP |
| Gene ID: | 4860 |
| Uniprot ID: | PNPH_HUMAN |
| Immunogen: | A synthetic peptide corresponding to a sequence in the middle region of human PNP, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids. |
| Function | Catalyzes the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. Preferentially acts on 6-oxopurine nucleosides including inosine and guanosine. |
| Protein Name | Purine Nucleoside PhosphorylasePnpInosine PhosphorylaseInosine-Guanosine Phosphorylase |
| Database Links | Reactome: R-HSA-6798695Reactome: R-HSA-74217Reactome: R-HSA-74259Reactome: R-HSA-9735763Reactome: R-HSA-9755088 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Purine Nucleoside Phosphorylase antibodyAnti-Pnp antibodyAnti-Inosine Phosphorylase antibodyAnti-Inosine-Guanosine Phosphorylase antibodyAnti-PNP antibodyAnti-NP antibody |
Information sourced from Uniprot.org