| Host: | Mouse |
| Applications: | ELISA/WB/ICC/IF/FACS |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal anti-PMVK (1-192aa) for use in ELISA, WB, ICC, IF and FACS in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | AT21C10 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2ak |
| Formulation: | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Purification: | By protein-A affinity chromatography |
| Concentration: | 1 mg/mL |
| Storage Instruction: | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PMVK |
| Gene ID: | 10654 |
| Uniprot ID: | PMVK_HUMAN |
| Immunogen Region: | 1-192aa |
| Accession Number: | NP_006547 |
| Immunogen: | Recombinant human PMVK (1-192aa) purified from E. coli |
| Tissue Specificity | Heart, liver, skeletal muscle, kidney, and pancreas. Lower level in brain, placenta and lung. |
| Function | Catalyzes the reversible ATP-dependent phosphorylation of mevalonate 5-phosphate to produce mevalonate diphosphate and ADP, a key step in the mevalonic acid mediated biosynthesis of isopentenyl diphosphate and other polyisoprenoid metabolites. |
| Protein Name | Phosphomevalonate KinasePmkaseHpmk |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Phosphomevalonate Kinase antibodyAnti-Pmkase antibodyAnti-Hpmk antibodyAnti-PMVK antibodyAnti-PMKI antibody |
Information sourced from Uniprot.org
