| Host: | Goat |
| Applications: | Pep-ELISA/WB |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-PMSCL1 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:64000.WB: Approx. 75kDa band observed in lysates of cell line Jurkat (calculated MW of 50.8kDa according to NP_001029366.1). The observed molecular weight corresponds to earlier findings in lite |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | EXOSC9 |
| Gene ID: | 5393 |
| Uniprot ID: | EXOS9_HUMAN |
| Immunogen Region: | C-Term |
| Accession Number: | NP_001029366.1; NP_005024.2 |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_001029366.1; NP_005024.2). |
| Immunogen Sequence: | RTQTTSAKQEKAP |
| Protein Name | Exosome Complex Component Rrp45Autoantigen Pm/Scl 1Exosome Component 9P75 Polymyositis-Scleroderma Overlap Syndrome-Associated AutoantigenPolymyositis/Scleroderma Autoantigen 1Polymyositis/Scleroderma Autoantigen 75 KdaPm/Scl-75 |
| Database Links | Reactome: R-HSA-380994Reactome: R-HSA-429958Reactome: R-HSA-450385Reactome: R-HSA-450513Reactome: R-HSA-450604Reactome: R-HSA-6791226 |
| Cellular Localisation | CytoplasmNucleusNucleolusNucleoplasmColocalizes With Setx In Nuclear Foci Upon Induction Of Transcription-Related Dna Damage At The S PhaseIsoform 1: NucleusIsoform 2: NucleusIsoform 3: NucleusExcluded From The Nucleolus |
| Alternative Antibody Names | Anti-Exosome Complex Component Rrp45 antibodyAnti-Autoantigen Pm/Scl 1 antibodyAnti-Exosome Component 9 antibodyAnti-P75 Polymyositis-Scleroderma Overlap Syndrome-Associated Autoantigen antibodyAnti-Polymyositis/Scleroderma Autoantigen 1 antibodyAnti-Polymyositis/Scleroderma Autoantigen 75 Kda antibodyAnti-Pm/Scl-75 antibodyAnti-EXOSC9 antibodyAnti-PMSCL1 antibody |
Information sourced from Uniprot.org
