Anti-PLPPR4 antibody (55-80 aa) (STJ192133)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein.the amino acid55-80
General Information
| Short Description | Rabbit polyclonal anti-Phospholipid phosphatase-related protein type 4 (55-80 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PLPPR4 |
| Gene ID | 9890 |
| Uniprot ID | PLPR4_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein.the amino acid55-80 |
| Immunogen Region | 55-80 aa |
| Specificity | LPPR4 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | O-glycosylated. Probably at Ser-346. |
| Function | Postsynaptic density membrane protein that indirectly regulates glutamatergic synaptic transmission through lysophosphatidic acid (LPA)-mediated signaling pathways. Binds lysophosphatidic acid (LPA) and mediates its internalization into cells. Could act as receptor or a transporter of this lipid at the post-synaptic membrane. Modulates lysophosphatidic acid (LPA) activity in neuron axonal outgrowth during development by attenuating phospholipid-induced axon collapse. |
| Protein Name | Phospholipid Phosphatase-Related Protein Type 4Brain-Specific Phosphatidic Acid Phosphatase-Like Protein 1Inactive 2-Lysophosphatidate Phosphatase Plppr4Lipid Phosphate Phosphatase-Related Protein Type 4Plasticity-Related Gene 1 ProteinPrg-1 |
| Database Links | Reactome: R-HSA-419408 |
| Cellular Localisation | Postsynaptic Density MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Phospholipid Phosphatase-Related Protein Type 4 antibodyAnti-Brain-Specific Phosphatidic Acid Phosphatase-Like Protein 1 antibodyAnti-Inactive 2-Lysophosphatidate Phosphatase Plppr4 antibodyAnti-Lipid Phosphate Phosphatase-Related Protein Type 4 antibodyAnti-Plasticity-Related Gene 1 Protein antibodyAnti-Prg-1 antibodyAnti-PLPPR4 antibodyAnti-KIAA0455 antibodyAnti-LPPR4 antibodyAnti-PHP1 antibodyAnti-PRG1 antibody |
Information sourced from Uniprot.org