| Short Description : | Rabbit polyclonal PLLP (1-100) antibody for use in WB, IF, ICC and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PLLP |
| Gene ID: | 51090 |
| Uniprot ID: | PLLP_HUMAN |
| Immunogen Region: | 1-100 |
| Immunogen Sequence: | MAEFPSKVSTRTSSPAQGAE ASVSALRPDLGFVRSRLGAL MLLQLVLGLLVWALIADTPY HLYPAYGWVMFVAVFLWLVT IVLFNLYLFQLHMKLYMVPW |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PLLP (NP_057077.1). |
| Post Translational Modifications | Phosphorylated. |
| Function | Main component of the myelin sheath that plays an important role in myelin membrane biogenesis and myelination. Plays an essential function in apical endocytosis. Regulates epithelial development through the regulation of apical endocytosis. Part of the intracellular machinery that mediates basolateral-to-apical transport of ICAM-1, an essential adhesion receptor in epithelial cells, from the subapical compartment in hepatic epithelial cells. |
| Protein Name | PlasmolipinPlasma Membrane Proteolipid |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinMyelin MembraneApical Cell MembraneGolgi ApparatusIn Polarized CellsLocalized Predominantly In The Apical MembraneLocated In Lipid RaftRecycled Between The Plasma Membrane And The Golgi ComplexPllp Is Continuously Recirculating In The Cell |
| Alternative Antibody Names | Anti-Plasmolipin antibodyAnti-Plasma Membrane Proteolipid antibodyAnti-PLLP antibodyAnti-PMLP antibodyAnti-TM4SF11 antibody |
Information sourced from Uniprot.org
