Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Perilipin-2 (300-437) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:100-1:500IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PLIN2 |
Gene ID: |
123 |
Uniprot ID: |
PLIN2_HUMAN |
Immunogen Region: |
300-437 |
Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 300-437 of human Perilipin-2 (NP_001113.2). |
Immunogen Sequence: |
SHCAEHIESRTLAIARNLTQ QLQTTCHTLLSNIQGVPQNI QDQAKHMGVMAGDIYSVFRN AASFKEVSDSLLTSSKGQLQ KMKESLDDVMDYLVNNTPLN WLVGPFYPQLTESQNAQDQG AEMDKSSQETQRSEHKTH |
Tissue Specificity | Milk lipid globules. |
Post Translational Modifications | Acylated.primarily with C14, C16 and C18 fatty acids. Phosphorylation at Tyr-232 by isoform 1 of CHKA (CHKalpha2) promotes dissociation from lipid droplets: dissociation is followed by recruitment of autophagosome machinery to lipid droplets and subsequent lipid droplet lipolysis. |
Function | Structural component of lipid droplets, which is required for the formation and maintenance of lipid storage droplets. |
Protein Name | Perilipin-2AdipophilinAdipose Differentiation-Related ProteinAdrp |
Database Links | Reactome: R-HSA-1989781Reactome: R-HSA-9613354Reactome: R-HSA-9613829Reactome: R-HSA-9615710 |
Cellular Localisation | MembranePeripheral Membrane ProteinLipid Droplet |
Alternative Antibody Names | Anti-Perilipin-2 antibodyAnti-Adipophilin antibodyAnti-Adipose Differentiation-Related Protein antibodyAnti-Adrp antibodyAnti-PLIN2 antibodyAnti-ADFP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance