Anti-PLEKHF1 antibody (STJA0008115)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PLEKHF1
General Information
| Short Description | Rabbit polyclonal anti-Pleckstrin homology domain-containing family F member 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PLEKHF1 |
| Gene ID | 79156 |
| Uniprot ID | PKHF1_HUMAN |
| Immunogen | Synthesized peptide derived from human PLEKHF1 |
| Specificity | This antibody detects endogenous levels of PLEKHF1 at Human, Mouse, Rat |
Additional Info
| Function | May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8. |
| Protein Name | Pleckstrin Homology Domain-Containing Family F Member 1Ph Domain-Containing Family F Member 1Lysosome-Associated Apoptosis-Inducing Protein Containing Ph And Fyve DomainsApoptosis-Inducing ProteinPh And Fyve Domain-Containing Protein 1Phafin-1Zinc Finger Fyve Domain-Containing Protein 15 |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmPerinuclear RegionLysosomeTranslocates To Lysosome During Apoptosis |
| Alternative Antibody Names | Anti-Pleckstrin Homology Domain-Containing Family F Member 1 antibodyAnti-Ph Domain-Containing Family F Member 1 antibodyAnti-Lysosome-Associated Apoptosis-Inducing Protein Containing Ph And Fyve Domains antibodyAnti-Apoptosis-Inducing Protein antibodyAnti-Ph And Fyve Domain-Containing Protein 1 antibodyAnti-Phafin-1 antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 15 antibodyAnti-PLEKHF1 antibodyAnti-APPD antibodyAnti-LAPF antibodyAnti-ZFYVE15 antibody |
Information sourced from Uniprot.org