| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Pleckstrin homology domain-containing family A member 3 (189-239 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PLEKHA3 |
| Gene ID: |
65977 |
| Uniprot ID: |
PKHA3_HUMAN |
| Immunogen Region: |
189-239 aa |
| Specificity: |
This antibody detects endogenous levels of PKHA3 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human PKHA3 at the amino acid range 189-239 |
| Function | Plays a role in regulation of vesicular cargo transport from the trans-Golgi network (TGN) to the plasma membrane. Regulates Golgi phosphatidylinositol 4-phosphate (PtdIns(4)P) levels and activates the PtdIns(4)P phosphatase activity of SACM1L when it binds PtdIns(4)P in 'trans' configuration. Binds preferentially to PtdIns(4)P. Negatively regulates APOB secretion from hepatocytes. |
| Protein Name | Pleckstrin Homology Domain-Containing Family A Member 3Ph Domain-Containing Family A Member 3Phosphatidylinositol-Four-Phosphate Adapter Protein 1Fapp-1Phosphoinositol 4-Phosphate Adapter Protein 1 |
| Database Links | Reactome: R-HSA-1660499 |
| Cellular Localisation | Golgi ApparatusTrans-Golgi Network MembranePeripheral Membrane ProteinLocalizes To Er-Trans Golgi Network (Tgn) Contacts Sites |
| Alternative Antibody Names | Anti-Pleckstrin Homology Domain-Containing Family A Member 3 antibodyAnti-Ph Domain-Containing Family A Member 3 antibodyAnti-Phosphatidylinositol-Four-Phosphate Adapter Protein 1 antibodyAnti-Fapp-1 antibodyAnti-Phosphoinositol 4-Phosphate Adapter Protein 1 antibodyAnti-PLEKHA3 antibodyAnti-FAPP1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
