Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-PLEKHA3 antibody (189-239 aa) (STJ195049)

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STJ195049
£48.00 - £252.00
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Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Pleckstrin homology domain-containing family A member 3 (189-239 aa) is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PLEKHA3
Gene ID: 65977
Uniprot ID: PKHA3_HUMAN
Immunogen Region: 189-239 aa
Specificity: This antibody detects endogenous levels of PKHA3 at Human/Mouse
Immunogen: Synthesized peptide derived from the human PKHA3 at the amino acid range 189-239
Function Plays a role in regulation of vesicular cargo transport from the trans-Golgi network (TGN) to the plasma membrane. Regulates Golgi phosphatidylinositol 4-phosphate (PtdIns(4)P) levels and activates the PtdIns(4)P phosphatase activity of SACM1L when it binds PtdIns(4)P in 'trans' configuration. Binds preferentially to PtdIns(4)P. Negatively regulates APOB secretion from hepatocytes.
Protein Name Pleckstrin Homology Domain-Containing Family A Member 3
Ph Domain-Containing Family A Member 3
Phosphatidylinositol-Four-Phosphate Adapter Protein 1
Fapp-1
Phosphoinositol 4-Phosphate Adapter Protein 1
Database Links Reactome: R-HSA-1660499
Cellular Localisation Golgi Apparatus
Trans-Golgi Network Membrane
Peripheral Membrane Protein
Localizes To Er-Trans Golgi Network (Tgn) Contacts Sites
Alternative Antibody Names Anti-Pleckstrin Homology Domain-Containing Family A Member 3 antibody
Anti-Ph Domain-Containing Family A Member 3 antibody
Anti-Phosphatidylinositol-Four-Phosphate Adapter Protein 1 antibody
Anti-Fapp-1 antibody
Anti-Phosphoinositol 4-Phosphate Adapter Protein 1 antibody
Anti-PLEKHA3 antibody
Anti-FAPP1 antibody

Information sourced from Uniprot.org

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