| Short Description : | Rabbit monoclonal Pleckstrin Homology Domain-Containing Family A Member 1 (300-404) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S4125RM |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:100-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PLEKHA1 |
| Gene ID: | 59338 |
| Uniprot ID: | PKHA1_HUMAN |
| Immunogen Region: | 300-404 |
| Immunogen Sequence: | SEHPPGPSESKHAFRPTNAA TATSHSTASRSNSLVSTFTM EKRGFYESLAKVKPGNFKVQ TVSPREPASKVTEQALLRPQ SKNGPQEKDCDLVDLDDASL PVSDV |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 300-404 of human TAPP1 (Q9HB21). |
| Tissue Specificity | Highly expressed in skeletal muscle, thymus, pancreas, placenta and lung. Detected at low levels in brain, heart, peripheral blood leukocytes, testis, ovary, spinal cord, thyroid, kidney, liver, small intestine and colon. |
| Function | Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. |
| Protein Name | Pleckstrin Homology Domain-Containing Family A Member 1Ph Domain-Containing Family A Member 1Tandem Ph Domain-Containing Protein 1Tapp-1 |
| Database Links | Reactome: R-HSA-1660499 |
| Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinNucleusLocates To The Plasma Membrane After Treatments That Stimulate The Production Of Ptdins34p2 |
| Alternative Antibody Names | Anti-Pleckstrin Homology Domain-Containing Family A Member 1 antibodyAnti-Ph Domain-Containing Family A Member 1 antibodyAnti-Tandem Ph Domain-Containing Protein 1 antibodyAnti-Tapp-1 antibodyAnti-PLEKHA1 antibodyAnti-TAPP1 antibody |
Information sourced from Uniprot.org
