• Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 30min).

Anti-PLEC antibody (240-320 aa) (STJ191170)

SKU:
STJ191170

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Plectin (240-320 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-300
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PLEC
Gene ID: 5339
Uniprot ID: PLEC_HUMAN
Immunogen Region: 240-320 aa
Specificity: PLEC Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 240-320
Post Translational Modifications Phosphorylated by CDK1.regulates dissociation from intermediate filaments during mitosis.
Function Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity.
Protein Name Plectin
Pcn
Pltn
Hemidesmosomal Protein 1
Hd1
Plectin-1
Database Links Reactome: R-HSA-2022090
Reactome: R-HSA-264870
Reactome: R-HSA-446107
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Junction
Hemidesmosome
Alternative Antibody Names Anti-Plectin antibody
Anti-Pcn antibody
Anti-Pltn antibody
Anti-Hemidesmosomal Protein 1 antibody
Anti-Hd1 antibody
Anti-Plectin-1 antibody
Anti-PLEC antibody
Anti-PLEC1 antibody

Information sourced from Uniprot.org

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