| Host: | Rabbit |
| Applications: | IHC/IF/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospholipase D1 (527-576 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | IHC 1:100-1:300 ELISA 1:5000 IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PLD1 |
| Gene ID: | 5337 |
| Uniprot ID: | PLD1_HUMAN |
| Immunogen Region: | 527-576 aa |
| Specificity: | PC-PLD1 Polyclonal Antibody detects endogenous levels of PC-PLD1 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human PLD1 at the amino acid range 527-576 |
| Function | Function as phospholipase selective for phosphatidylcholine. Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic. |
| Protein Name | Phospholipase D1 Pld 1 Hpld1 Choline Phosphatase 1 Phosphatidylcholine-Hydrolyzing Phospholipase D1 |
| Database Links | Reactome: R-HSA-1483148 Reactome: R-HSA-1483166 Reactome: R-HSA-2029485 Reactome: R-HSA-6798695 Reactome: R-HSA-8980692 Reactome: R-HSA-9013148 Reactome: R-HSA-9013149 Reactome: R-HSA-9013408 |
| Cellular Localisation | Cytoplasm Perinuclear Region Endoplasmic Reticulum Membrane Lipid-Anchor Cytoplasmic Side Golgi Apparatus Membrane Late Endosome Membrane |
| Alternative Antibody Names | Anti-Phospholipase D1 antibody Anti-Pld 1 antibody Anti-Hpld1 antibody Anti-Choline Phosphatase 1 antibody Anti-Phosphatidylcholine-Hydrolyzing Phospholipase D1 antibody Anti-PLD1 antibody |
Information sourced from Uniprot.org