| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PLCH1 (1100-1400) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:3000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
PLCH1 |
| Gene ID: |
23007 |
| Uniprot ID: |
PLCH1_HUMAN |
| Immunogen Region: |
1100-1400 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1100-1400 of human PLCH1 (NP_055811.1). |
| Immunogen Sequence: |
LEGNRGKGRAATSFSLSDVS MLCSDIPDLHSTAILQESVI SHLIDNVTLTNENEPGSSIS ALIGQFDETNNQALTVVSHL HNTSVMSGHCPLPSLGLKMP IKHGFCKGKSKSSFLCSSPE LIALSSSETTKHATNTVYET TCTPISKTKPDDDLSSKAKT AALESNLPGSPNTSRGWLPK SPTKGEDWETLKSCSPASSP DLTLEDVIADPTLCFNSGES SLVEIDGESENLSLTTCEY |
| Tissue Specificity | Expressed in brain and to a lower extent in lung. In brain, it is found in cerebrum, cerebellum and spinal cord. In embryo expressed in the notochord, developing spinal cord (in a ventral to dorsal gradient), dorsal root ganglia, cerebellum and dermatomyosome. |
| Function | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calcium-activated phosphatidylinositol-specific phospholipase C enzymes. |
| Protein Name | 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Eta-1Phosphoinositide Phospholipase C-Eta-1Phospholipase C-Eta-1Plc-Eta-1Phospholipase C-Like Protein 3Plc-L3 |
| Database Links | Reactome: R-HSA-1855204 |
| Cellular Localisation | CytoplasmMembrane |
| Alternative Antibody Names | Anti-1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Eta-1 antibodyAnti-Phosphoinositide Phospholipase C-Eta-1 antibodyAnti-Phospholipase C-Eta-1 antibodyAnti-Plc-Eta-1 antibodyAnti-Phospholipase C-Like Protein 3 antibodyAnti-Plc-L3 antibodyAnti-PLCH1 antibodyAnti-KIAA1069 antibodyAnti-PLCL3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
