| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:1000-1:3000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PLCH1 |
| Gene ID: | 23007 |
| Uniprot ID: | PLCH1_HUMAN |
| Immunogen Region: | 1100-1400 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1100-1400 of human PLCH1 (NP_055811.1). |
| Immunogen Sequence: | LEGNRGKGRAATSFSLSDVS MLCSDIPDLHSTAILQESVI SHLIDNVTLTNENEPGSSIS ALIGQFDETNNQALTVVSHL HNTSVMSGHCPLPSLGLKMP IKHGFCKGKSKSSFLCSSPE LIALSSSETTKHATNTVYET TCTPISKTKPDDDLSSKAKT AALESNLPGSPNTSRGWLPK SPTKGEDWETLKSCSPASSP DLTLEDVIADPTLCFNSGES SLVEIDGESENLSLTTCEY |
| Tissue Specificity | Expressed in brain and to a lower extent in lung. In brain, it is found in cerebrum, cerebellum and spinal cord. In embryo expressed in the notochord, developing spinal cord (in a ventral to dorsal gradient), dorsal root ganglia, cerebellum and dermatomyosome. |
| Function | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calcium-activated phosphatidylinositol-specific phospholipase C enzymes. |
| Protein Name | 1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Eta-1Phosphoinositide Phospholipase C-Eta-1Phospholipase C-Eta-1Plc-Eta-1Phospholipase C-Like Protein 3Plc-L3 |
| Database Links | Reactome: R-HSA-1855204 |
| Cellular Localisation | CytoplasmMembrane |
| Alternative Antibody Names | Anti-1-Phosphatidylinositol 4 -5-Bisphosphate Phosphodiesterase Eta-1 antibodyAnti-Phosphoinositide Phospholipase C-Eta-1 antibodyAnti-Phospholipase C-Eta-1 antibodyAnti-Plc-Eta-1 antibodyAnti-Phospholipase C-Like Protein 3 antibodyAnti-Plc-L3 antibodyAnti-PLCH1 antibodyAnti-KIAA1069 antibodyAnti-PLCL3 antibody |
Information sourced from Uniprot.org