Anti-PLAAT2 antibody (1-51 aa) (STJ197686)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human HRSL2 at the amino acid range 1-51
General Information
| Short Description | Rabbit polyclonal anti-Phospholipase A and acyltransferase 2 (1-51 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PLAAT2 |
| Gene ID | 54979 |
| Uniprot ID | PLAT2_HUMAN |
| Immunogen | Synthesized peptide derived from the human HRSL2 at the amino acid range 1-51 |
| Immunogen Region | 1-51 aa |
| Specificity | This antibody detects endogenous levels of human HRSL2 |
Additional Info
| Function | Exhibits both phospholipase A1/2 and acyltransferase activities. Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids. For most substrates, PLA1 activity is much higher than PLA2 activity. Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid. Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE), which serves as precursor for N-acylethanolamines (NAEs). Catalyzes N-acylation of PE using both sn-1 and sn-2 palmitoyl groups of PC as acyl donor. Exhibits high phospholipase A1/2 activity and low N-acyltransferase activity. |
| Protein Name | Phospholipase A And Acyltransferase 2 Hras-Like Suppressor 2 |
| Database Links | Reactome: R-HSA-1482839 |
| Cellular Localisation | CytoplasmMembraneSingle-Pass Membrane ProteinExhibits A Granular Pattern In The Cytoplasm With Preferential Perinuclear Localization |
| Alternative Antibody Names | Anti-Phospholipase A And Acyltransferase 2 antibodyAnti-Hras-Like Suppressor 2 antibodyAnti-PLAAT2 antibodyAnti-HRASLS2 antibody |
Information sourced from Uniprot.org