Anti-PLA1A antibody (381-430 aa) (STJ95148)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PLA1A at the amino acid range 381-430
General Information
| Short Description | Rabbit polyclonal anti-Phospholipase A1 member A (381-430 aa) for use in WB, IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PLA1A |
| Gene ID | 51365 |
| Uniprot ID | PLA1A_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PLA1A at the amino acid range 381-430 |
| Immunogen Region | 381-430 aa |
| Specificity | PLA1A Polyclonal Antibody detects endogenous levels of PLA1A protein. |
Additional Info
| Function | Hydrolyzes the ester bond of the acyl group attached at the sn-1 position of phosphatidylserines (phospholipase A1 activity) and 1-acyl-2-lysophosphatidylserines (lysophospholipase activity) in the pathway of phosphatidylserines acyl chain remodeling. Cleaves phosphatidylserines exposed on the outer leaflet of the plasma membrane of apoptotic cells producing 2-acyl-1-lysophosphatidylserines, which in turn enhance mast cell activation and histamine production. Has no activity toward other glycerophospholipids including phosphatidylcholines, phosphatidylethanolamines, phosphatidic acids or phosphatidylinositols, or glycerolipids such as triolein. Isoform 2: Hydrolyzes lyso-PS but not PS. |
| Protein Name | Phospholipase A1 Member APhosphatidylserine-Specific Phospholipase A1Ps-Pla1 |
| Database Links | Reactome: R-HSA-1482801 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Phospholipase A1 Member A antibodyAnti-Phosphatidylserine-Specific Phospholipase A1 antibodyAnti-Ps-Pla1 antibodyAnti-PLA1A antibodyAnti-NMD antibodyAnti-PSPLA1 antibody |
Information sourced from Uniprot.org