Host: |
Rabbit |
Applications: |
WB/IHC/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Phospholipase A1 member A (381-430 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IHC 1:100-1:300ELISA 1:5000IF 1:50-200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PLA1A |
Gene ID: |
51365 |
Uniprot ID: |
PLA1A_HUMAN |
Immunogen Region: |
381-430 aa |
Specificity: |
PLA1A Polyclonal Antibody detects endogenous levels of PLA1A protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human PLA1A at the amino acid range 381-430 |
Function | Hydrolyzes the ester bond of the acyl group attached at the sn-1 position of phosphatidylserines (phospholipase A1 activity) and 1-acyl-2-lysophosphatidylserines (lysophospholipase activity) in the pathway of phosphatidylserines acyl chain remodeling. Cleaves phosphatidylserines exposed on the outer leaflet of the plasma membrane of apoptotic cells producing 2-acyl-1-lysophosphatidylserines, which in turn enhance mast cell activation and histamine production. Has no activity toward other glycerophospholipids including phosphatidylcholines, phosphatidylethanolamines, phosphatidic acids or phosphatidylinositols, or glycerolipids such as triolein. Isoform 2: Hydrolyzes lyso-PS but not PS. |
Protein Name | Phospholipase A1 Member APhosphatidylserine-Specific Phospholipase A1Ps-Pla1 |
Database Links | Reactome: R-HSA-1482801 |
Cellular Localisation | Secreted |
Alternative Antibody Names | Anti-Phospholipase A1 Member A antibodyAnti-Phosphatidylserine-Specific Phospholipase A1 antibodyAnti-Ps-Pla1 antibodyAnti-PLA1A antibodyAnti-NMD antibodyAnti-PSPLA1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance