Anti-PITPNB antibody (20-69 aa) (STJ95103)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PITPNB at the amino acid range 20-69
STJ95103
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General Information

Short DescriptionRabbit polyclonal anti-Phosphatidylinositol transfer protein beta isoform (20-69 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA/IHC
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolPITPNB
Gene ID23760
Uniprot IDPIPNB_HUMAN
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PITPNB at the amino acid range 20-69
Immunogen Region20-69 aa
SpecificityPITP Beta Polyclonal Antibody detects endogenous levels of PITP Beta protein.

Additional Info

Post Translational Modifications Constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity but is required for Golgi targeting.
Function Catalyzes the transfer of phosphatidylinositol and phosphatidylcholine between membranes. Also catalyzes the transfer of sphingomyelin. Required for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum.phosphatidylinositol and phosphatidylcholine transfer activity is essential for this function.
Protein Name Phosphatidylinositol Transfer Protein Beta Isoform
Pi-Tp-Beta
Ptdins Transfer Protein Beta
Ptdinstp Beta
Database Links Reactome: R-HSA-1483196
Cellular Localisation Golgi Apparatus
Golgi Apparatus Membrane
Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Phosphatidylinositol Transfer Protein Beta Isoform antibody
Anti-Pi-Tp-Beta antibody
Anti-Ptdins Transfer Protein Beta antibody
Anti-Ptdinstp Beta antibody
Anti-PITPNB antibody

Information sourced from Uniprot.org

Citations

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