Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Type 2 phosphatidylinositol 4, 5-bisphosphate 4-phosphatase (33-83 aa) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
PIP4P2 |
Gene ID: |
55529 |
Uniprot ID: |
PP4P2_HUMAN |
Immunogen Region: |
33-83 aa |
Specificity: |
This antibody detects endogenous levels of TM55A at Human/Mouse/Rat |
Immunogen: |
Synthesized peptide derived from the human TM55A at the amino acid range 33-83 |
Function | Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate. Negatively regulates the phagocytosis of large particles by reducing phagosomal phosphatidylinositol 4,5-bisphosphate accumulation during cup formation. |
Protein Name | Type 2 Phosphatidylinositol 4 -5-Bisphosphate 4-PhosphataseType 2 Ptdins-4 -5-P2 4-PtasePtdins-4 -5-P2 4-Ptase IiTransmembrane Protein 55a |
Cellular Localisation | Late Endosome MembraneMulti-Pass Membrane ProteinLysosome MembraneCytoplasmic VesiclePhagosome MembraneCell Membrane |
Alternative Antibody Names | Anti-Type 2 Phosphatidylinositol 4 -5-Bisphosphate 4-Phosphatase antibodyAnti-Type 2 Ptdins-4 -5-P2 4-Ptase antibodyAnti-Ptdins-4 -5-P2 4-Ptase Ii antibodyAnti-Transmembrane Protein 55a antibodyAnti-PIP4P2 antibodyAnti-TMEM55A antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance