| Short Description : | Rabbit polyclonal anti-Phosphatidylinositol 5-phosphate 4-kinase type-2 gammaP 4-kinase type II gamma (262-312 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA/IHC |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PIP4K2C |
| Gene ID: | 79837 |
| Uniprot ID: | PI42C_HUMAN |
| Immunogen: | Synthesized peptide derived from the human PI42C at the amino acid range 262-312 |
| Immunogen Region: | 262-312 aa |
| Specificity: | This antibody detects endogenous levels of PI42C at Human/Mouse/Rat |
| Function | Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity. PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism. They interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3. |
| Protein Name | Phosphatidylinositol 5-Phosphate 4-Kinase Type-2 GammaPhosphatidylinositol 5-Phosphate 4-Kinase Type Ii GammaPi(5p 4-Kinase Type Ii GammaPip4kii-Gamma |
| Database Links | Reactome: R-HSA-1660499Reactome: R-HSA-6811555Reactome: R-HSA-6811558Reactome: R-HSA-8847453 |
| Cellular Localisation | Endoplasmic ReticulumCytoplasm |
| Alternative Antibody Names | Anti-Phosphatidylinositol 5-Phosphate 4-Kinase Type-2 Gamma antibodyAnti-Phosphatidylinositol 5-Phosphate 4-Kinase Type Ii Gamma antibodyAnti-Pi(5p 4-Kinase Type Ii Gamma antibodyAnti-Pip4kii-Gamma antibodyAnti-PIP4K2C antibodyAnti-PIP5K2C antibody |
Information sourced from Uniprot.org
