Host: | Mouse |
Applications: | WB/IHC/ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Short Description : | Mouse monoclonal antibody anti-Collagen Alpha-1 (Met1-Glu92) is suitable for use in Western Blot, Immunohistochemistry and ELISA research applications. |
Clonality : | Monoclonal |
Clone ID : | 2F2 |
Conjugation: | Unconjugated |
Isotype: | IgG1 |
Formulation: | 0.01M PBS |
Purification: | Protein G purified from mice ascites |
Concentration: | 1 mg/mL |
Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Gene Symbol: | COL1A1 |
Gene ID: | 1277 |
Uniprot ID: | CO1A1_HUMAN |
Immunogen Region: | Met1-Glu92 |
Immunogen: | E coli-derived recombinant Human PINP (Met1-Glu92) |
Post Translational Modifications | Contains mostly 4-hydroxyproline. Proline residues at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. Contains 3-hydroxyproline at a few sites. This modification occurs on the first proline residue in the sequence motif Gly-Pro-Hyp, where Hyp is 4-hydroxyproline. Lysine residues at the third position of the tripeptide repeating unit (G-X-Y) are 5-hydroxylated in some or all of the chains. O-glycosylated on hydroxylated lysine residues. The O-linked glycan consists of a Glc-Gal disaccharide. |
Function | Type I collagen is a member of group I collagen (fibrillar forming collagen). |
Protein Name | Collagen Alpha-1(I ChainAlpha-1 Type I Collagen |
Database Links | Reactome: R-HSA-114604Reactome: R-HSA-1442490Reactome: R-HSA-1474244Reactome: R-HSA-1650814Reactome: R-HSA-198933Reactome: R-HSA-2022090Reactome: R-HSA-202733Reactome: R-HSA-216083Reactome: R-HSA-2214320Reactome: R-HSA-2243919Reactome: R-HSA-3000170Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-3000480Reactome: R-HSA-430116Reactome: R-HSA-75892Reactome: R-HSA-76009Reactome: R-HSA-8874081Reactome: R-HSA-8940973Reactome: R-HSA-8948216Reactome: R-HSA-9845619Reactome: R-HSA-9845620Reactome: R-HSA-9845621Reactome: R-HSA-9845622Reactome: R-HSA-9846298 |
Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
Alternative Antibody Names | Anti-Collagen Alpha-1(I Chain antibodyAnti-Alpha-1 Type I Collagen antibodyAnti-COL1A1 antibody |
Information sourced from Uniprot.org