| Short Description : | Mouse monoclonal Paired Immunoglobulin-Like Type 2 Receptor Alpha antibody for use in ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | ELISA |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
| Clonality : | Monoclonal |
| Clone ID : | SAA1628 |
| Isotype: | IgG2a |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | Protein A/G purified from cell culture supernatant |
| Formulation: | 0.01M PBS, pH 7.4. |
| Storage Instruction: | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
| Gene Symbol: | PILRA |
| Gene ID: | 29992 |
| Uniprot ID: | PILRA_HUMAN |
| Post Translational Modifications | N- and O-glycosylated. only N-glycosylated. Phosphorylated on tyrosine residues. |
| Function | Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRA is thought to act as a cellular signaling inhibitory receptor by recruiting cytoplasmic phosphatases like PTPN6/SHP-1 and PTPN11/SHP-2 via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules. Receptor for PIANP. (Microbial infection) Acts as an entry co-receptor for herpes simplex virus 1. |
| Protein Name | Paired Immunoglobulin-Like Type 2 Receptor AlphaCell Surface Receptor Fdf03Inhibitory Receptor Pilr-Alpha |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Cell MembraneIsoform 3: SecretedIsoform 4: Secreted |
| Alternative Antibody Names | Anti-Paired Immunoglobulin-Like Type 2 Receptor Alpha antibodyAnti-Cell Surface Receptor Fdf03 antibodyAnti-Inhibitory Receptor Pilr-Alpha antibodyAnti-PILRA antibody |
Information sourced from Uniprot.org
