| Host: | Rabbit |
| Applications: | WB/IHC/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phosphoinositide 3-kinase regulatory subunit 5 (695-744 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000IF 1:50-200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PIK3R5 |
| Gene ID: | 23533 |
| Uniprot ID: | PI3R5_HUMAN |
| Immunogen Region: | 695-744 aa |
| Specificity: | PI 3-kinase p101 Polyclonal Antibody detects endogenous levels of PI 3-kinase p101 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human PIK3R5 at the amino acid range 695-744 |
| Function | Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG. |
| Protein Name | Phosphoinositide 3-Kinase Regulatory Subunit 5Pi3-Kinase Regulatory Subunit 5Pi3-Kinase P101 SubunitPhosphatidylinositol 4 -5-Bisphosphate 3-Kinase Regulatory SubunitPtdins-3-Kinase Regulatory SubunitProtein Foap-2Ptdins-3-Kinase P101P101-Pi3k |
| Database Links | Reactome: R-HSA-114604Reactome: R-HSA-1257604Reactome: R-HSA-1660499Reactome: R-HSA-2219530Reactome: R-HSA-389357Reactome: R-HSA-392451Reactome: R-HSA-6811558Reactome: R-HSA-9027276Reactome: R-HSA-9927354 |
| Cellular Localisation | NucleusCytoplasmCell MembranePeripheral Membrane ProteinPredominantly Localized In The Nucleus In Absence Of Pik3cg/P120Colocalizes With Pik3cg/P120 In The CytoplasmTranslocated To The Plasma Membrane In A Beta-Gamma G Protein-Dependent Manner |
| Alternative Antibody Names | Anti-Phosphoinositide 3-Kinase Regulatory Subunit 5 antibodyAnti-Pi3-Kinase Regulatory Subunit 5 antibodyAnti-Pi3-Kinase P101 Subunit antibodyAnti-Phosphatidylinositol 4 -5-Bisphosphate 3-Kinase Regulatory Subunit antibodyAnti-Ptdins-3-Kinase Regulatory Subunit antibodyAnti-Protein Foap-2 antibodyAnti-Ptdins-3-Kinase P101 antibodyAnti-P101-Pi3k antibodyAnti-PIK3R5 antibody |
Information sourced from Uniprot.org
