| Tissue Specificity | Ubiquitously expressed with high expression in fetal brain compared to adult brain. Abundant expression is observed in cerebellum, cerebral cortex, cerebral meninges, and vermis cerebelli. |
| Function | Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG. |
| Protein Name | Phosphoinositide 3-Kinase Regulatory Subunit 5Pi3-Kinase Regulatory Subunit 5Pi3-Kinase P101 SubunitPhosphatidylinositol 4 -5-Bisphosphate 3-Kinase Regulatory SubunitPtdins-3-Kinase Regulatory SubunitProtein Foap-2Ptdins-3-Kinase P101P101-Pi3k |
| Database Links | Reactome: R-HSA-114604Reactome: R-HSA-1660499Reactome: R-HSA-392451Reactome: R-HSA-9027276 |
| Cellular Localisation | NucleusCytoplasmCell MembranePeripheral Membrane ProteinPredominantly Localized In The Nucleus In Absence Of Pik3cg/P120Colocalizes With Pik3cg/P120 In The CytoplasmTranslocated To The Plasma Membrane In A Beta-Gamma G Protein-Dependent Manner |
| Alternative Antibody Names | Anti-Phosphoinositide 3-Kinase Regulatory Subunit 5 antibodyAnti-Pi3-Kinase Regulatory Subunit 5 antibodyAnti-Pi3-Kinase P101 Subunit antibodyAnti-Phosphatidylinositol 4 -5-Bisphosphate 3-Kinase Regulatory Subunit antibodyAnti-Ptdins-3-Kinase Regulatory Subunit antibodyAnti-Protein Foap-2 antibodyAnti-Ptdins-3-Kinase P101 antibodyAnti-P101-Pi3k antibodyAnti-PIK3R5 antibody |
Information sourced from Uniprot.org
