| Function | Alpha-1,2-mannosyltransferase that catalyzes the transfer of the fourth mannose, via an alpha-1,2 bond, from a dolichol-phosphate-mannose (Dol-P-Man) to an alpha-D-Man-(1->2)-alpha-D-Man-(1->6)-2-PEtn-alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol (also termed H6) intermediate and participates in the twelfth step of the glycosylphosphatidylinositol-anchor biosynthesis. The presence of a fourth mannose in GPI is facultative, suggesting that it only exists in some tissues. |
| Protein Name | Gpi Alpha-1 -2-Mannosyltransferase 4Gpi Mannosyltransferase IvGpi-Mt-IvPhosphatidylinositol-Glycan Biosynthesis Class Z ProteinPig-ZSmp3 HomologHsmp3 |
| Database Links | Reactome: R-HSA-162710 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Gpi Alpha-1 -2-Mannosyltransferase 4 antibodyAnti-Gpi Mannosyltransferase Iv antibodyAnti-Gpi-Mt-Iv antibodyAnti-Phosphatidylinositol-Glycan Biosynthesis Class Z Protein antibodyAnti-Pig-Z antibodyAnti-Smp3 Homolog antibodyAnti-Hsmp3 antibodyAnti-PIGZ antibodyAnti-SMP3 antibody |
Information sourced from Uniprot.org
