Anti-PIGX antibody (80-220) (STJ117655)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PIGX (80-220) antibody for use in WB and ELISA in rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PIGX |
| Gene ID | 54965 |
| Uniprot ID | PIGX_HUMAN |
| Immunogen Region | 80-220 |
| Immunogen Sequence | LIKQDIPAGLYVDPYELASL RERNITEAVMVSENFDIEAP NYLSKESEVLIYARRDSQCI DCFQAFLPVHCRYHRPHSED GEASIVVNNPDLLMFCDQEF PILKCWAHSEVAAPCALENE DICQWNKMKYKSVYKNVILQ V |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 80-220 of human PIGX (NP_060331.3). |
Additional Info
| Function | Stabilizing subunit of the glycosylphosphatidylinositol-mannosyltransferase I complex which catalyzes the transfer of the first mannose, via an alpha-1,4 bond from a dolichol-phosphate-mannose (Dol-P-Man) to the glucosaminyl acyl phosphatidylinositol (GlcN-(acyl)PI) intermediate to generate alpha-D-Man-(1->4)-alpha-D-GlcN-(1->6)-(1-radyl,2-acyl-sn-glycero-3-phospho)-2-acyl-inositol and participates in the sixth step of the glycosylphosphatidylinositol-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase PIGM. |
| Protein Name | Gpi Alpha-1 -4-Mannosyltransferase I - Stabilizing SubunitPhosphatidylinositol-Glycan Biosynthesis Class X ProteinPig-X |
| Database Links | Reactome: R-HSA-162710 |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Gpi Alpha-1 -4-Mannosyltransferase I - Stabilizing Subunit antibodyAnti-Phosphatidylinositol-Glycan Biosynthesis Class X Protein antibodyAnti-Pig-X antibodyAnti-PIGX antibody |
Information sourced from Uniprot.org