| Short Description : | Rabbit polyclonal PI4KA (1780-1860) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PI4KA |
| Gene ID: | 5297 |
| Uniprot ID: | PI4KA_HUMAN |
| Immunogen Region: | 1780-1860 |
| Immunogen Sequence: | PEAIVLDIDYKSGTPMQSAA KAPYLAKFKVKRCGVSELEK EGLRCRSDSEDECSTQEADG QKISWQAAIFKVGDDCRQDM L |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1780-1860 of human PI4KA (P42356). |
| Tissue Specificity | Expressed ubiquitously. Highest levels in placenta and brain. Little or no expression in lung, liver, pancreas, testis or leukocytes. |
| Function | Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate. |
| Protein Name | Phosphatidylinositol 4-Kinase AlphaPi4-Kinase AlphaPi4k-AlphaPtdins-4-Kinase AlphaPhosphatidylinositol 4-Kinase Iii Alpha |
| Database Links | Reactome: R-HSA-1483248Reactome: R-HSA-1660514 |
| Cellular Localisation | CytoplasmCell MembraneLocalization To The Plasma Membrane Is Mediated By The Pi4k Complex And Association With Efr3 (Efr3a Or Efr3b)Ttc7 (Ttc7a Or Ttc7b) And Hycc (Hycc1 Or Hycc2)Localization To The Plasma Membrane Is Regulated By Tmem150a |
| Alternative Antibody Names | Anti-Phosphatidylinositol 4-Kinase Alpha antibodyAnti-Pi4-Kinase Alpha antibodyAnti-Pi4k-Alpha antibodyAnti-Ptdins-4-Kinase Alpha antibodyAnti-Phosphatidylinositol 4-Kinase Iii Alpha antibodyAnti-PI4KA antibodyAnti-PIK4 antibodyAnti-PIK4CA antibody |
Information sourced from Uniprot.org
