• Immunohistochemistry analysis of paraffin-embedded human brain, using Tryptophan Hydroxylase (Phospho-Ser58) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of lysates from 293 cells treated with paclitaxel 1uM 24h, using Tryptophan Hydroxylase (Phospho-Ser58) Antibody. The lane on the right is blocked with the phospho peptide.
  • Western blot analysis of 293 cells using Phospho-TPH1 (S58) Polyclonal Antibody

Anti-Phospho-TPH1-Ser58 antibody (26-75 aa) (STJ90907)

SKU:
STJ90907

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Tryptophan 5-hydroxylase 1-Ser58 (26-75 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: TPH1
Gene ID: 7166
Uniprot ID: TPH1_HUMAN
Immunogen Region: 26-75 aa
Specificity: Phospho-TPH1 (S58) Polyclonal Antibody detects endogenous levels of TPH1 protein only when phosphorylated at S58.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Tryptophan Hydroxylase around the phosphorylation site of Ser58 at the amino acid range 26-75
Post Translational Modifications Ubiquitinated, leading to its degradation by the proteasome. Ubiquitinated is triggered by phosphorylation. Phosphorylated.triggering degradation by the proteasome.
Function Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis.
Protein Name Tryptophan 5-Hydroxylase 1
Tryptophan 5-Monooxygenase 1
Database Links Reactome: R-HSA-209931
Reactome: R-HSA-9031628
Alternative Antibody Names Anti-Tryptophan 5-Hydroxylase 1 antibody
Anti-Tryptophan 5-Monooxygenase 1 antibody
Anti-TPH1 antibody
Anti-TPH antibody
Anti-TPRH antibody
Anti-TRPH antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance